Scientist (Histology)
AstraZeneca

Job Info

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Scientist

Do you have expertise in, and passion for Oncology? Would you like to apply your expertise to impact the patient in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

AstraZeneca discovers and develops medicines in 4 core areas of Oncology, Respiratory and Immunology (R&I), and Cardiovascular, Renal and Metabolic Disease (CVRM). Oncology Safety, a global department within the Clinical Pharmacology and Safety Sciences (CPSS) function, is looking for an experienced histology technician to join their teams to develop and advance our portfolio of innovative anti-cancer medicines in Oncology R&D. As an histology technician you will work at the forefront of experimental pathology and safety science, working in a multidisciplinary environment where you will help progress a rich and diverse pipeline which includes small molecules, cutting-edge mAb-based therapeutics, antibody conjugates, next generation cellular and viral therapies.

Job Summary:
We are seeking an outstanding scientist experienced in histology to join our CPSS Pathology team. The successful candidate will provide support to the safety assessment of toxicity, pharmacodynamic, and efficacy animal studies in an exciting collaborative team environment. Specific activities for this role include routine histology techniques (tissue processing, embedding, microtomy, and staining), immunohistochemistry, and advanced molecular techniques.

Responsibilities:

• Activities include tissue trimming, dehydration, infiltration, embedding, microtomy, mounting and sectioning of paraffin tissue blocks, preparing high quality microscope slides for pathology assessment.
  
• Perform histochemical and immunohistochemical stains on a variety of preclinical study tissues using automated staining platforms (i.e. Ventana).
  
• Develop immunohistochemical protocols to investigate mechanisms of toxicity
  
• Prepare and maintain all necessary lab instruments and reagents, including stains, alcohols, and paraffins according to proper specifications.
  
• Maintain digital archive of stained slides by scanning and using Aperio eSlide Manager and digital laboratory notebook
  
• Perform image analysis using HALO imaging software in collaboration with pathologists and present data to project safety teams
  

Requirements/ Qualifications:

• Minimum bachelor's degree in biological sciences
  
• >1 year relevant histology experience
  
• Ability to manage multiple projects while maintaining high-quality slide production
  
• Excellent communication skills, enthusiastic, self-motivating
  
• Ability to work and effectively communicate in a local and global team environment
  

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey!

So, what's next!

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!

Where can I find out more?

Follow AstraZeneca on LinkedInhttps://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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