Post-Doctoral Fellow
University of Colorado Anschutz Medical Campus

Aurora, Colorado

Posted in Education and Training


Job Info


Post-Doctoral Fellow - 28736 Faculty

Description
University of Colorado Anschutz Medical Campus

Department: Medicine – Pulmonary Sciences and Critical Care

Job Title: Post-Doctoral Fellow

Position #:00655220 – Requisition #:28736

Job Summary:

The Schwartz/Yang laboratory uses genome editing approaches to manipulate genetic variants and expression of key gens in primary cell and animal models. Computational approaches include genetic screens for genes that interact with MUC5B, identification of biomarkers of early disease, and single cell and spatial transcriptomic technologies. The ultimate goal is to understand the early mechanisms of lung fibrosis, develop biomarkers for early detection, use MUC5B to identify key pathogenic mechanisms in lung fibrosis, and ultimately identify therapeutics for early treatment of disease.

Multiple postdoctoral positions are available for highly motivated candidates to join the research program of Drs. David Schwartz and Ivana Yang at the University of Colorado Anschutz Medical Campus. Drs. Schwartz and Yang conduct cutting-edge basic and translational research in pulmonary fibrosis, focusing on genetics, genomics, epigenetics, animal models, and molecular determinants of human pulmonary fibrosis. Their group identified a gain-of-function genetic variant in the airway mucin MUC5B as the key predisposition factor for development of early and established forms of pulmonary fibrosis and are now pursuing projects in functional genomics. Current funded projects include:

Mechanism regulating lung injury and early lung fibrosis with an emphasis on MUC5B, ER stress, apoptosis, cilia function and mucus clearance, and biophysical dysfunction of distal airway epithelia.

Characterization of novel animal model of MUC5B-induced fibrosis.

Investigation of genes and transcripts that interact with MUC5B in diversity outbred mice.

Role of IncRNAs in modifying the genetic susceptibility in pulmonary fibrosis.

Central role of MUC5B in the molecular drivers of usual interstitial pneumonia.

Whole genome sequence analysis in patients with idiopathic pulmonary fibrosis.

Biomarkers of early interstitial lung disease.

Why Join Us:

The Division of Pulmonary Sciences and Critical Care Medicine strives to create a welcoming and inclusive environment, engage with diverse perspectives through a growth mindset, and maximize the success and inclusion of all trainees, staff, and faculty. We are committed to creating a healthy work environment that values and promotes well-being of our trainees, staff, and faculty. Though we are a large division, we are continuously fostering our supportive community that values diversity and inclusion.

We are very proud of our long and illustrious history. Many seminal discoveries in pulmonary and critical care medicine occurred here in Denver, including advances in tuberculosis, interstitial lung disease, airway disease, cancer, and critical care. Many of our former trainees have taken leadership roles in academic medicine, including Division and Department Chairs, Deans, and American Thoracic Society Presidents.

The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, holidays, and more. To see what benefits are available, please visit https://www.cu.edu/employee-services/benefits-wellness.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty, and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

    PhD in life sciences such as molecular biology, cell biology, or related field. PhD must be conferred prior to starting position but need not be completed at time of application.

Preferred Qualifications:
    The applicant must have documented training and experience in molecular/cell biology and/or animal models. A working knowledge of molecular biology.

Knowledge, Skills, and Abilities:
    The applicant should be motivated, maintain methodic and careful work practices, have interest in learning new skills and knowledge, have excellent communication skills, be able to have flexible work schedule as required for completion of study goals and enjoy teamwork. The successful applicant is expected to have an ability to work independently, a strong work ethic and a commitment to becoming an independent scientist with excellent skills in scientific writing.



How to Apply:

For full consideration, please submit the following document(s):
    A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position Curriculum vitae / Resume Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Nancy Miller at nancy.j.miller@cuanschutz.edu or Christina Moldenhauer at christina.moldenhauer@cuanschutz.edu



Screening of Applications Begins:

Immediately and continues until position is filled. For best consideration, apply by March 1, 2023.



Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE: $54,840 to $75,000.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu​.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date. Information regarding this requirement, and exemptions can be found at:

Anschutz: https://apptrkr.com/get_redirect.php?id=3819765&targetURL=

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Unit-Specific Exemptions:
    Anschutz Campus – Accommodations may be granted for medical or religious reasons.



The University of Colorado seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty, and staff of diverse backgrounds.


Qualifications
Application Materials Required: Cover Letter, Resume/CV, List of References

Job Category: Faculty

Primary Location: Aurora Department: U0001 -- DENVER & ANSCHUTZ MED CAMPUS - 20219 - SOM-MED-PUL GENERAL OPERATIONS

Schedule: Full-time

Posting Date: Jan 20, 2023

Unposting Date: Ongoing Posting Contact Name: Christina Moldenhauer Posting Contact Email: christina.moldenhauer@cuanschutz.edu Position Number: 00655220





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