Post-Doc Research Associate
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina

Posted in Education and Training


This job has expired.

Job Info


Department:

Genetics - 423501

Posting Open Date:

04/13/2022

Application Deadline:

06/24/2022

Open Until Filled:

No

Position Type:

Postdoctoral Scholar

Position Title:

Post-Doc Research Associate

Vacancy ID:

PDS003435

Full-time/Part-time:

Full-Time Temporary

Hours per week:

40

FTE:

1

Work Location:

Chapel Hill, NC

Position Location:

North Carolina, US

Hiring Range:

Dependent on Qualifications

Proposed Start Date:

05/23/2022

Estimated Duration of Appointment:

12 Months

Primary Purpose of Organizational Unit:

The mission of the Genetics department is to provide basic and applied genetic/genomic research, education, and training at the interface between biology, chemistry, physics, computer science, mathematics, the social sciences, public health and medicine in order to have a profound effect on how medicine will be practiced in the future.

Our graduate programs train students to be creative, sophisticated research scientists prepared to pursue careers focused on genetics and genomics working in academic science, government, or commercial positions. Students conduct their dissertation research using diverse experimental approaches - from classical genetics to the most modern molecular methods - to address a broad range of contemporary problems in biomedical science.

The Department also includes a clinical arm focused on medical genetics, which covers the broad spectrum of clinical genetic research from disease prevention to diagnosis and treatment. This specialty includes evaluation, mutation discovery, counseling and risk assessment through analysis and genetic testing. Locating the clinical group alongside basic scientists facilitates integration of cutting-edge genetic research with patient care.

Position Summary:

The Shpargel Laboratory in the University of North Carolina Genetics Department is seeking a postdoctoral scholar to lead a R01 funded project studying the impact of enhancer chromatin activation factors on facial development and neural crest stem cell biology. The histone methylases, demethylases, acetylases, and reader proteins that catalyze and translate enhancer activation events are mutated in a wide array of human developmental craniofacial disorders. We utilize a variety of mouse genetic and cell culture models in combination with the latest genomic editing and sequencing methodologies to understand the cellular and molecular functions of histone modifying enzymes at the genome level with respect to human disorders. Current projects are examining the roles of these enzymes in balancing stem cell maintenance with osteoblast and chondrocyte differentiation. We are utilizing gene editing technology and proteomics to explore the novel non-catalytic function of chromatin modifiers in enhancer activation. Apply now to join an exciting, collaborative research environment utilizing technologies at the forefront of genetic and genomic exploration.
Lab website: https://shpargellab.web.unc.edu/
Department website: https://www.med.unc.edu/genetics/

Minimum Education and Experience Requirements:

Ph.D. in Genetics, Genomics, Developmental Biology, or a related discipline.

Required Qualifications, Competencies, and Experience:

Experience in developmental biology, mammalian cell culture, and molecular biology.

Preferred Qualifications, Competencies, and Experience:

A strong background in developmental biology, mammalian cell culture, and molecular biology is preferred.

Special Instructions:

For information on UNC Postdoctoral Benefits and Services click here


This job has expired.

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